Honestly after talking with retired NYPD officers, almost all will say the same thing. In a self defense situation, the perp is usually less than 18 feet away, and you have rougly than 2 seconds to react, draw, and fire, let alone really aim. (if they rush you, in the first second they will be rougly 10 feet or less away from you) The officer who taught me defensive shooting showed me how to draw and fire using your finger like you are pointing your finger at the aggressor to establish aim, then to squeeze to shoot at the center of mass.
However, it's a good idea to have a stronger front sight for target shooting reasons. Follow up shots will be faster to acquire in theory.