I would say use this gun how you would any other LEM. Personally, the safety will go on to holster the gun and then come off and remain off until the gun needs to be holstered again. As long as the safety doesn't get in the way of me shooting accurately, I'll leave it on because I think it's kinda cool to have a rare USP with ambi safety. If it gets in the way, I'll remove it and shoot the gun like all of my other hammer fired HK's (which are LEM without safety).
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