If you plan on shooting it regularly, the .9 is far more economical to practice with. And .9 defense ammo has came a long way in the past twenty years.
I love my tactical. 45. Only wish i could feed it better and enjoy it more.
Both are extremely good choices, but as always, get one you can afford to practice with. That's my opinion, Of Course. .
9mm will have a slightly smaller grip (and overall will be smaller), if you've got smaller hands. Mags are cheaper, ammo will be cheaper... .45 will probably be better to suppress since most .45 is subsonic. And the .45 Tactical has been around much longer the 9 Tactical.
Personally, I have a Mark 23 for my full (or perhaps past full) sized .45, and a USP Tactical 9mm, and don't feel the need for a USP Tactical .45. If you can afford the Mark 23, I say go for it, there's not a single handgun I can shoot nearly as well as it (USP Tactical included).
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